Transcript-Specific Expression Profiles Derived from Sequence-Based Analysis of Standard Microarrays
نویسندگان
چکیده
منابع مشابه
Transcript-Specific Expression Profiles Derived from Sequence-Based Analysis of Standard Microarrays
BACKGROUND Alternative mRNA processing mechanisms lead to multiple transcripts (i.e. splice isoforms) of a given gene which may have distinct biological functions. Microarrays like Affymetrix GeneChips measure mRNA expression of genes using sets of nucleotide probes. Until recently probe sets were not designed for transcript specificity. Nevertheless, the re-analysis of established microarray d...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0004702